Voyager DP-263-S Guía de usuario descargar pdf (Pagina 308)

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Chapter 5 Optimizing Instrument Settings

5-78 PerSeptive Biosystems

A lower Accelerating Voltage setting does the following:

• Provides more data points across a peak for better peak

definition when analyzing low mass ions (Linear mode

only).

• Improves resolution when analyzing compounds below

2,000 Da, and the resolution is limited by the digitization

rate of the system (Reflector mode).

5.4.4.3 Setting Guide Wire Voltage%

To optimize sensitivity, you can adjust the Guide Wire

Voltage%:

• Linear mode—Increase in increments of 0.05 percent

until you see signal-to-noise ratio start to decrease.

• Reflector mode—Increase in increments of

0.01 percent. Settings above 0.05 percent do not typically

improve signal-to-noise ratio.

NOTE: In Reflector mode, Guide Wire Voltage% also affects

mass resolution. To fine tune signal-to-noise ratio and

resolution at the same time, adjust the Guide Wire Voltage%

in increments smaller than 0.01 percent.

For more

information

For more information, see:

• Section 5.4.3.3, Optimizing Guide Wire Voltage%

• Section 5.3.4, Understanding Guide Wire Voltage%

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Voyager DP-263-S Guía de usuario Pagina 308

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